Group Members

Reza Nejadnik - image

Reza Nejadnik

Principal investigator

Reza Received his PhD from the University of Groningen in the Netherlands in 2009. Following a few years of research in the area of proteins, nano and biomaterials at The University of Texas, Northwestern University and Radboud University Nijmegen, Reza joined the Leiden Academic Center for Drug Research in order to co-lead a European public-private partnership project (COMPACT) that addressed the current challenges with formulation and delivery of macromolecules. In the 4-year period of the COMPACT project, Reza’s research focused on characterization and understanding of protein aggregation in complex formulations as well as protein-material interactions. Reza then joined the Global Biologic Drug Product Development team of Sanofi and headed a formulation and process development laboratory in the Company’s R&D hub in Frankfurt, Germany. He developed early formulations and drug product manufacturing processes for several molecules in various modalities including antibodies and nanobodies. Reza is currently a faculty member of the Department of Pharmaceutical Sciences and Experimental Therapeutics.

Sina

Sina Sarsarshahi

postdoctoral researcher

Sina received his PhD diploma in Malignant Diseases from the Medical University of Vienna (MUW) in 2021. His PhD project focused on modifying radiation-induced inflammatory/proliferative signaling by immunomodulatory compounds. Since July 2023, he works in Nejadnik Laboratory as a postdoctoral fellow to investigate the immunogenicity of protein therapeutic compounds, their degradation products and effects of various molecular modifications in in-vitro and in-vivo models.

Welcome!

Sanghati Bhattacharya

postdoctoral researcher

Sanghati received her PhD in molecular cytogenetics and bioinformatics on plant hemoglobin genes and proteins from the University of North Bengal, India, in 2018. Soon after that, she received an Institute Post-doctoral Fellowship (IPDF) and started working on therapeutic proteomics at the Indian Institute of Technology, Delhi (IITD), India. Her experience encompasses multiple liquid chromatography-mass spectrometry-based projects that convey biotherapeutic assessments by pushing the workflow towards next-generation separation, applying multi-attribute methods with fewer individual runs, evaluating the critical quality attributes of biotherapeutics, evaluating the similarity of Indian marketed drug products, and assessing higher order structure alteration under different stress scenarios. She is a postdoctoral scholar in Nejadnik Laboratory since November 2023 and is working on new problems to learn and understand the fundamental complex biological mixtures to be separated and the immunogenicity of biotherapeutics. Outside of research, she enjoys traveling to new places.

parham

Parham Parnian

postdoctoral researcher

Parham received his PhD in Chemical and Biochemical Engineering at the University of Iowa in 2023, where his research focused on developing non-invasive thermal treatments for controlling biofilm infections on medical implants. In November 2023, Parham joined Nejadnik Laboratory and the Center for Biocatalysis and Bioprocessing as a postdoctoral research scholar. In his current role, Parham is engaged in developing and optimizing experimental developability models for various proteins in addition to contributing to the creation of a database of biomanufacturing capabilities in the State of Iowa.

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Siddhanth Hejmady

Graduate student

Siddhanth Hejmady received his Bachelor of Pharmacy from the University of Mumbai, India in 2017 and his Master of Pharmacy with specialisation in Pharmaceutics from the Birla Institute of Technology and Science, Pilani, India in 2020. Siddhanth worked as a Formulation Scientist developing complex generic products of small molecules in the Cipla R&D Center, Mumbai before joining the graduate program at the Department of Pharmaceutical Sciences and Experimental Therapeutics at the University of Iowa. His current research work involves characterization of protein therapeutics and formulating biopharmaceuticals.

Hesham

Hesham Refaat

Graduate student

Hesham received his Bachelor of Pharmaceutical Sciences and his Master of Pharmaceutics and Drug Delivery from Minia University in 2016 and 2020 respectively. Hesham worked as a production pharmacist in a sterile manufacturing facility in Cairo, Egypt. After that, He shifted to academia and worked as a teaching associate in the pharmaceutics department at Deraya University where he conducted his research on enhancing the delivery of compounds from natural sources before joining the graduate program at the Department of Pharmaceutical Sciences and Experimental Therapeutics at the University of Iowa. His current research work involves characterization and formulation of proteins and biosimilar products.

Eman Kamel

Eman Kamel

Graduate student

Eman received a Bachelor of Pharmaceutical Sciences and a Master of Pharmaceutics and Clinical Pharmacy from Minia University, Egypt in 2013 and 2018 respectively. After graduation in 2013, Eman joined the Department of Pharmaceutics and Clinical Pharmacy, Minia University as an associate lecturer. Eman has ample experiences working with cells including but not limited to cell culturing and freezing, cytotoxicity and viability assays, transfection and cell uptake studies. She also has performed translational research in the area of cancer nanomedicine while working as a visiting scholar at the Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, USA before joining the graduate program at the same department.

Former Members

Yusra Rahman

Yusra Rahman

postdoctoral researcher (2021-2024)

Ysura has joined KUMC as a postdoctoral researcher in the Liskin Swint-Kruse Lab. She will focus her research on the evolution of protein functional variation to drive advances in personalized medicine.

Elham

Elham Taherian

Graduate student (2022-2024)

Elham has joined Salem lab as a graduate student. She will focus on drug delivery and nanotechnology.